Let Intellipharm make you more efficient in selecting and developing drug products, saving you time and money.

OUR MISSION:

  • Contribute to the science of drug delivery through the development of mechanistically based models for the prediction of drug dissolution, precipitation, absorption, gastrointestinal motility, and metabolism
  • Promote open source code for building physiologically based pharmacokinetic models through education and training
  • Establish drug particle size specifications to optimize drug dissolution and content uniformity through simulations backed by experimental validation

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The first true polydisperse model was developed by Hintz and Johnson …

Wang et al., J Pharm Sci (2015) 104:2998-3017

Concerning the oral absorption modeling, the dissolution was best described by the Johnson model …

Gruber et al., Cancer Chemother Pharmacol (2018) 81:763-771

Dissolution

The world’s best dissolution model for polydisperse drug powders

Maximum Absorbable Dose

One of the most widely used simple models for assessing drug developability

Gastrointestinal Motility

Intellipharm uses the multiple moving plug (MMP) model to simulate gastrointestinal motility. The MMP model is the most realistic in terms of both mechanism and physiology.